Biomedical Applications of Peptide-, Glyco- and Glycopeptide by Jaroslav Sebestik, Milan Reinis, Jan Jezek

By Jaroslav Sebestik, Milan Reinis, Jan Jezek

Dendrimers are again and again branched and approximately round huge molecules. they are often utilized in a number of scientific functions, comparable to anticancer polymeric nanomedicines and nanocarriers, gene vendors and vectors in gene supply, distinction brokers for molecular imaging and vaccines opposed to infectious illnesses and melanoma. The hugely branched, multivalent nature and molecular structure of dendrimers lead them to perfect instruments for quite a few tissue engineering purposes. This booklet describes varied different types of dendrimers, their biomedical and physico-chemical functions in addition to convergent and divergent syntheses, click on chemistry and ligation concepts. it's a wealthy resource of knowledge for researchers in biochemistry and pharmacology engaged on drug improvement in addition to for natural chemists who're engaged in synthesis of dendrimers.

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Chem. 18(14), 2060–2078 (2011) 31. : Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications. Drug Discov. Today 6(8), 427–436 (2001) 32. : Glycopeptide dendrimers: tuning carbohydrate-lectin interactions with amino acids. Mol. BioSyst. 7(2), 411–421 (2011) 33. : Detailed nomenclature for dendritic molecules. New J. Chem. 30(1), 32–43 (2006) 34. : Glycans: Bioactive signals decoded by lectins. Biochem. Soc. Trans. 36(6), 1491–1496 (2008) 35. : From lectin structure to functional glycomics: principles of the sugar code.

1–26. Wiley, New York (2011) 54. : Water-soluble glycodendrimers: Synthesis and stabilization of catalytically active Pd and Pt nanoparticles. Tetrahedron Lett. 52(16), 1842–1846 (2011) 55. : Synthesis of glycopolymers for microarray applications via ligation of reducing sugars to a poly(acryloyl hydrazide) scaffold. J. Am. Chem. Soc. 132(29), 9963–9965 (2010) 56. : Synthesis and AFM studies of lectin-carbohydrate self-assemblies. Tetrahedron 64(30–31), 7331–7337 (2008) 57. : Single-walled carbon nanotube as a unique scaffold for the multivalent display of sugars.

Drug Discov. Today 6(8), 427–436 (2001) 45. : Glycopeptide dendrimers: tuning carbohydrate-lectin interactions with amino acids. Mol. BioSyst. 7(2), 411–421 (2011) 46. : Synthesis of glycopeptide dendrimers, dimerization and affinity for concanavalin A. Bioorg. Med. Chem. 19(9), 2879–2887 (2011) 47. : Water-soluble CdSe nanoparticles stabilised by dense-shell glycodendrimers. New J. Chem. 33(4), 703–706 (2009) 48. : Solid-phase synthesis of peptide and glycopeptide thioesters through side-chain-anchoring strategies.

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Biomedical Applications of Peptide-, Glyco- and Glycopeptide by Jaroslav Sebestik, Milan Reinis, Jan Jezek
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