Artificial Heart 2: Proceedings of the 2nd International by Tetsuzo Akutsu, Hitoshi Koyanagi, Setsuo Takatani, Kazunori

By Tetsuzo Akutsu, Hitoshi Koyanagi, Setsuo Takatani, Kazunori Kataoka, Jack G. Copeland, Stuart L. Cooper, Peer M. Portner, David B. Geselowitz

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Extra info for Artificial Heart 2: Proceedings of the 2nd International Symposium on Artificial Heart and Assist Device, August 13–14, 1987, Tokyo, Japan

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The procedure of the ex vivo A V shunt in a rabbit is illustrated in Fig. 1. Results and discussion First, we performed the in vitro thrombosis test on the copolymer surfaces using recalcified PRP. 2. Results of the in vitro simulation test of thrombosis on PPO-segmented nylon 610 surfaces 10 Vl a; Thrombosis time (min) Code (11 0 a. Nylon 610 61P3-25 61P3-47 u ..... (11 3(11 ...... u 0 10 '- LL.. (/) 0 a; 0 10 20 30 Time (min ) Fig. 2. Representative curves of platelet elution from polymer columns.

This is a similar trend to that observed in air. These results may indicate that absorption of lipids under cyclic straining did not induce the reduction in fatigue strength. Lipids which absorbed and diffused into hard-segment domains during the long-term exposure to the lipid solution were the cause of the reduced fatigue strength. Influence of Hydrolytic Enzymes on Fatigue Strength ofSPUU Enzymes are able to catalyze the degradation of synthetic polymers. Cell-polymer interactions may lead to cellular activation and enhanced enzyme exocytosis by the inflammatory cells (12].

10. References 1. Lehal MD , Cooper SL (1986) Polyurethanes in medicine. CRC, Boca Raton 2. Kashiwagi T, Ito Y, Kang IK, Sisido M, Imanishi Y (1985) Synthesis of fluorinated polyurethane and its evaluation as antithrombogenic material. Polym Prepr Jpn 34: 582 (in Japanese) 3. Kashiwagi T, Ito Y, Sisido M , Imanishi Y (1987) Syn- 11 . 12. thesis of fluorinated polyurethane and its evaluation as antithrombogenic material. Polym Prepr Jpn 36: 818 (in Japanese) Kawamura Y, Ito Y, Sisido M, Imanishi Y (1986) Synthesis of polyetherurethaneurea bearing long fluoroalkyl chains in the soft segments, its oxygen permeability and antithrombogenicity.

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Artificial Heart 2: Proceedings of the 2nd International by Tetsuzo Akutsu, Hitoshi Koyanagi, Setsuo Takatani, Kazunori
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