By Robert Flanagan, Alison Jones, Robert L Maynard
Antidotesprovides updated info at the improvement, their proposed mechanism of motion, toxicity, availability and useful points in their scientific use. The antidotes mentioned are essentially these both in present use, or into account or improvement. The publication comprises info at the antidotal therapy of poisoning with compounds encountered not just in Western Europe, North the USA and Australia, but additionally in constructing nations. It covers resource, shelf lifestyles and situations the place antidote management complicates or compromises laboratory research.
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Extra resources for Antidotes: Principles and Clinical Applications
International opinion concerning indications, safety and availability of poison centre antidotes and treatment. Hum Toxicol 1987; 6: 361–4. Swann JP. The universal drug: theriac through the ages. Med Heritage 1985; 1: 456–8. Taylor AS. On Poisons in Relation to Medical Jurisprudence and Medicine, 2nd edn. London: J Churchill, 1859: 1–5. Thienes CH, Haley TJ. Clinical Toxicology, 4th edn. London: Kimpton, 1964: 99. Tichy W. Poisons: Antidotes and Anecdotes. New York: Sterling, 1977. Trestrail JH.
Animaux Venimeux et Venins: La Fonction Venimeuse Chez Tous les Animaux; les Appareils Venimeux, les Venins et Leurs Propriétés; les Fonctions et Usages des Venins; l’Envenimation et Son Traitement, Volumes 1 and 2. Paris: Masson, 1922: 759–62. Picchioni AL. Activated charcoal: a neglected antidote. Pediatr Clin N Am 1970; 17: 535–43. Plaitakis A, Duvoisin RC. : physiologic antidote to stramonium poisoning. Clin Neuropharmacol 1983; 6: 1–5. 32 ■ GENERAL INTRODUCTION ■ 33 ■ CHAPTER 1 ■ Prescott LF, Newton RW, Swainson CP, Wright N, Forrest ARW, Matthew H.
When needed, the ferrous sulphate solution was mixed with eight times its bulk of water and the charcoal/magnesia mixture added with constant stirring. This concoction was to be administered in wineglass-full doses in cases of poisoning with arsenic, zinc, opium, digitalis, mercury or strychnine. It was said to be useless in poisoning with antimony, caustic alkalis or phosphorus, but efficacy against other poisons seems unlikely. A similar preparation, the so-called ‘universal antidote’, originated in the USA in the 1940s and was said to adsorb/neutralize ingested poisons.
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